ロード中...
Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody
The N-glycans attached to the Fab and Fc domains play distinct roles in modulating the functions of antibodies. However, posttranslational site-selective modifications of glycans in antibodies and other multiply glycosylated proteins remain a challenging task. Here, we report a chemoenzymatic method...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6255169/ https://ncbi.nlm.nih.gov/pubmed/30397147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812833115 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|