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Chemoenzymatic glyco-engineering of monoclonal antibodies

Monoclonal antibodies (mAbs) are an important class of therapeutic glycoproteins widely used for the treatment of cancer, inflammation, and infectious diseases. Compelling data have shown that the presence and fine structures of the conserved N-glycans at the Fc domain can profoundly affect the effe...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Giddens, John P., Wang, Lai-Xi
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851427/
https://ncbi.nlm.nih.gov/pubmed/26082235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2760-9_25
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