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Glyco-engineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation
The presence and precise structures of the glycans attached at the Fc domain of monoclonal antibodies play an important role in determining antibody's effector functions such as antibody-dependent cell cytotoxicity (ADCC), complement activation, and anti-inflammatory activity. This paper descri...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628294/ https://ncbi.nlm.nih.gov/pubmed/18771295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800874y |
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