Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags

[Image: see text] Glycoproteins with chemically defined glycosylation sites and structures are important biopharmaceutical targets and critical tools for glycobiology. One approach toward constructing such molecules involves chemical glycosylation of aldehyde-tagged proteins. Here, we report the ins...

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Bibliographic Details
Main Authors: Smith, Elizabeth L., Giddens, John P., Iavarone, Anthony T., Godula, Kamil, Wang, Lai-Xi, Bertozzi, Carolyn R.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004622/
https://ncbi.nlm.nih.gov/pubmed/24702330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500061s
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