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Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies

Chemoenzymatic glycan remodeling of antibodies using an endoglycosidase and its mutant is emerging as an attractive approach for producing homogeneous antibody glycoforms. We report in this paper a site-specific covalent immobilization of the endoglycosidases (Endo-S2 and its glycosynthase mutant D1...

詳細記述

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書誌詳細
出版年:Carbohydr Res
主要な著者: Li, Tiezheng, Li, Chao, Quan, David N., Bentley, William E., Wang, Lai-Xi
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837956/
https://ncbi.nlm.nih.gov/pubmed/29475193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.02.007
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