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Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies
Chemoenzymatic glycan remodeling of antibodies using an endoglycosidase and its mutant is emerging as an attractive approach for producing homogeneous antibody glycoforms. We report in this paper a site-specific covalent immobilization of the endoglycosidases (Endo-S2 and its glycosynthase mutant D1...
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Publicado no: | Carbohydr Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837956/ https://ncbi.nlm.nih.gov/pubmed/29475193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.02.007 |
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