Increased mitochondrial biogenesis and ROS production accompany prolonged CD4(+) T cell activation

Activation of CD4(+) T cells to proliferate, drives cells towards aerobic glycolysis for energy production while using mitochondria primarily for macromolecular synthesis. In addition, the mitochondria of activated T cells increase production of reactive oxygen species (ROS) providing an important s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Akkaya, Billur, Roesler, Alexander S., Miozzo, Pietro, Theall, Brandon P., Souz, Jafar Al, Smelkinson, Margery G., Kabat, Juraj, Traba, Javier, Sack, Michael N., Brzostowski, Joseph A., Pena, Mirna, Dorward, David W., Pierce, Susan K., Akkaya, Munir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246812/
https://ncbi.nlm.nih.gov/pubmed/30373851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800753
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi