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Increased mitochondrial biogenesis and ROS production accompany prolonged CD4(+) T cell activation
Activation of CD4(+) T cells to proliferate, drives cells towards aerobic glycolysis for energy production while using mitochondria primarily for macromolecular synthesis. In addition, the mitochondria of activated T cells increase production of reactive oxygen species (ROS) providing an important s...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6246812/ https://ncbi.nlm.nih.gov/pubmed/30373851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800753 |
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