Increased mitochondrial biogenesis and ROS production accompany prolonged CD4(+) T cell activation

Activation of CD4(+) T cells to proliferate, drives cells towards aerobic glycolysis for energy production while using mitochondria primarily for macromolecular synthesis. In addition, the mitochondria of activated T cells increase production of reactive oxygen species (ROS) providing an important s...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Akkaya, Billur, Roesler, Alexander S., Miozzo, Pietro, Theall, Brandon P., Souz, Jafar Al, Smelkinson, Margery G., Kabat, Juraj, Traba, Javier, Sack, Michael N., Brzostowski, Joseph A., Pena, Mirna, Dorward, David W., Pierce, Susan K., Akkaya, Munir
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246812/
https://ncbi.nlm.nih.gov/pubmed/30373851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800753
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