T regulatory cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells

T regulatory cells (T(regs)) can activate multiple suppressive mechanisms in vitro upon activation via the T cell receptor resulting in antigen-independent suppression. However, it remains unclear whether similar pathways operate in vivo. Here, we found that antigen-specific T(regs) activated by den...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Akkaya, Billur, Oya, Yoshihiro, Akkaya, Munir, Souz, Jafar Al, Holstein, Amanda H., Kamenyeva, Olena, Kabat, Juraj, Matsumura, Ryutaro, Dorward, David W., Glass, Deborah D., Shevach, Ethan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402611/
https://ncbi.nlm.nih.gov/pubmed/30643268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0280-2
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