B cells produce type 1 interferons in response to the Toll-like receptor 9 agonist CpG-A conjugated to cationic lipids

B cells express the innate receptor, toll-like receptor 9 (TLR9), which signals in response to unmethylated CpG sequences in microbial DNA. Of the two major classes of CpG-containing oligonucleotides, CpG-A appears restricted to inducing type 1 interferon (type 1 IFN) in innate immune cells and CpG-...

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Udgivet i:J Immunol
Main Authors: Akkaya, Munir, Akkaya, Billur, Miozzo, Pietro, Rawat, Mukul, Pena, Mirna, Sheehan, Patrick W., Kim, Ann S., Kamenyeva, Olena, Kabat, Juraj, Bolland, Silvia, Chaturvedi, Akanksha, Pierce, Susan K.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531204/
https://ncbi.nlm.nih.gov/pubmed/28652397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700348
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