Toll-like receptor 9 antagonizes antibody affinity maturation

Key events in T cell-dependent antibody responses, including affinity maturation, are dependent on the B cell’s presentation of antigen to helper T cells at critical check points in germinal center formation in secondary lymphoid organs. Here we show that Toll-like receptor 9 (TLR9) signaling blocke...

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Bibliografski detalji
Izdano u:Nat Immunol
Glavni autori: Akkaya, Munir, Akkaya, Billur, Kim, Ann S., Miozzo, Pietro, Sohn, Haewon, Pena, Mirna, Roesler, Alexander S., Theall, Brandon P., Henke, Travis, Kabat, Juraj, Lu, Jinghua, Dorward, David W., Dahlstrom, Eric, Skinner, Jeff, Miller, Louis H., Pierce, Susan K.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839995/
https://ncbi.nlm.nih.gov/pubmed/29476183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0052-z
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