Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis

OBJECTIVE: Osteoarthritis (OA) is the most prevalent joint disease. As disease-modifying therapies are not available, novel therapeutic targets need to be discovered and prioritized for their importance in mediating the abnormal phenotype of cells in OA-affected joints. Here, we generated a genome-w...

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Publicado no:Osteoarthritis Cartilage
Main Authors: Fisch, Kathleen M., Gamini, Ramya, Alvarez-Garcia, Oscar, Akagi, Ryuichiro, Saito, Masahiko, Muramatsu, Yuta, Sasho, Takahisa, Koziol, James A., Su, Andrew I., Lotz, Martin K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245598/
https://ncbi.nlm.nih.gov/pubmed/30081074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2018.07.012
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