Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy

Eitemau Tebyg

• REDD1 deficiency impairs autophagy and mitochondrial biogenesis in articular cartilage and increases the severity of experimental osteoarthritis
  gan: Alvarez-Garcia, Oscar, et al.
  Cyhoeddwyd: (2017)
• Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis
  gan: Akasaki, Yukio, et al.
  Cyhoeddwyd: (2015)
• FoxO transcription factors influence cartilage maturation, homeostasis and osteoarthritis pathogenesis by modulating autophagy and proteoglycan 4
  gan: Matsuzaki, Tokio, et al.
  Cyhoeddwyd: (2018)
• Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis
  gan: Fisch, Kathleen M., et al.
  Cyhoeddwyd: (2018)
• The relationship of autophagy defects and cartilage damage during joint aging in a mouse model
  gan: Caramés, Beatriz, et al.
  Cyhoeddwyd: (2015)