Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis

OBJECTIVE: Aging is a major risk factor for osteoarthritis (OA). Forkhead-box class O (FoxO) transcription factors regulate mechanisms of cellular aging, including protein quality control, autophagy and defenses against oxidative stress. The objective of this study was to analyze FoxO transcription...

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Bibliographic Details
Main Authors: Akasaki, Y., Hasegawa, A., Saito, M., Asahara, H., Iwamoto, Y., Lotz, M.K.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932989/
https://ncbi.nlm.nih.gov/pubmed/24269635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2013.11.004
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