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FOXO transcription factors support oxidative stress resistance in human chondrocytes
OBJECTIVES: A major signaling pathway that regulates cellular aging is the Insulin/IGF-1/Pl3k/Akt/forkhead-box class O (FOXO) transcription factor axis. Previously, we observed that FOXO factors are dysregulated in aged and OA cartilage. The objective of this study was to investigate the impact of d...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254812/ https://ncbi.nlm.nih.gov/pubmed/25186470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38868 |
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