Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens

BACKGROUND: In humans and other animals, the chronic hypoxic response is mediated by hypoxia inducible transcription factors (HIFs) which regulate the expression of genes that counteract the effects of limiting oxygen. Prolyl hydroxylases (PHDs) act as hypoxia sensors for the HIF system in organisms...

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Bibliografische gegevens
Gepubliceerd in:Hypoxia (Auckl)
Hoofdauteurs: Lippl, Kerstin, Boleininger, Anna, McDonough, Michael A, Abboud, Martine I, Tarhonskaya, Hanna, Chowdhury, Rasheduzzaman, Loenarz, Christoph, Schofield, Christopher J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235002/
https://ncbi.nlm.nih.gov/pubmed/30519597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S174655
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