Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

Cellular and physiological responses to changes in dioxygen levels in metazoans are mediated via the posttranslational oxidation of hypoxia-inducible transcription factor (HIF). Hydroxylation of conserved prolyl residues in the HIF-α subunit, catalyzed by HIF prolyl-hydroxylases (PHDs), signals for...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: McDonough, Michael A., Li, Vivian, Flashman, Emily, Chowdhury, Rasheduzzaman, Mohr, Christopher, Liénard, Benoît M. R., Zondlo, James, Oldham, Neil J., Clifton, Ian J., Lewis, Jeffrey, McNeill, Luke A., Kurzeja, Robert J. M., Hewitson, Kirsty S., Yang, Evelyn, Jordan, Steven, Syed, Rashid S., Schofield, Christopher J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2006
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502536/
https://ncbi.nlm.nih.gov/pubmed/16782814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601283103
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items