EXTH-58. ONC206, AN IMIPRIDONE FAMILY MEMBER, SUPPRESSES GLIOBLASTOMA CELLS VIA BLOCKING CANCER STEMNESS PATHWAYS

INTRODUCTION: Imipridones selectively target G protein-coupled receptors (GPCRs) that control critical signaling pathways in various cancer cells. Aberrant overexpression of GPCRs has been implicated in tumorigenesis. ONC201, a first generation imipridone that directly antagonizes dopamine receptor...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Jung, Jinkyu, Dowdy, Tyrone, Tabouret, Emeline, Reynolds, Brent, Allen, Joshua, Larion, Mioara, Gilbert, Mark, Park, Deric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
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Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217271/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.406
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