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DDIS-06. ONC206, AN IMIPRIDONE FAMILY MEMBER, SUPPRESSES GLIOMA STEM CELL MAINTENANCE
INTRODUCTION: Imipridones selectively target G protein-coupled receptors (GPCRs) that control critical signaling pathways in various cancer cells. Aberrant overexpression of GPCRs has been implicated in tumorigenesis. ONC201, a first generation imipridone that directly antagonizes dopamine receptor...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692117/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.242 |
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