DDRE-33. MOLECULAR DIFFERENTIATION OF IMIPRIDONES ONC201 AND ONC206

ONC201 is the first bitopic antagonist of dopamine receptor D2 (DRD2) and agonist of ClpP in oncology. In clinical trials, the small molecule has induced durable tumor regressions and clinical benefit in H3 K27M-mutant glioma patients while being well tolerated. ONC206 is a chemical derivative of ON...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Prabhu, Varun, Cuoco, Caroline, Jung, Jinkyu, Morrow, Sara, Kawakibi, Abed Rahman, Willette, Blair, Day, Marilyn, Anantharaman, Lakshmi, Charter, Neil, Rucker, Joseph, Doranz, Benjamin, Basken, Joel, Stogniew, Martin, Gilbert, Mark, Free, R, Sibley, David, Allen, Joshua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Drug Discovery, Drug Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650915/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.278
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