DDRE-33. MOLECULAR DIFFERENTIATION OF IMIPRIDONES ONC201 AND ONC206

ONC201 is the first bitopic antagonist of dopamine receptor D2 (DRD2) and agonist of ClpP in oncology. In clinical trials, the small molecule has induced durable tumor regressions and clinical benefit in H3 K27M-mutant glioma patients while being well tolerated. ONC206 is a chemical derivative of ON...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Prabhu, Varun, Cuoco, Caroline, Jung, Jinkyu, Morrow, Sara, Kawakibi, Abed Rahman, Willette, Blair, Day, Marilyn, Anantharaman, Lakshmi, Charter, Neil, Rucker, Joseph, Doranz, Benjamin, Basken, Joel, Stogniew, Martin, Gilbert, Mark, Free, R, Sibley, David, Allen, Joshua
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
Drug Discovery, Drug Resistance
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650915/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.278
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料