EXTH-43. DIFFERENTIATED PHARMACOLOGY OF THE IMIPRIDONE ONC201, THE FIRST SELECTIVE DRD2/3 ANTAGONIST IN CLINICAL NEURO-ONCOLOGY

Por Madhukar, Neel, Prabhu, Varun Vijay, Anantharaman, Lakshmi, Sulli, Chidananda, Davidson, Edgar, Deacon, Sean, Tarapore, Rohinton, Rucker, Joseph, Charter, Neil, Doranz, Benjamin, Oster, Wolfgang, Elemento, Olivier, Free, R Benjamin, Sibley, David, Allen, Joshua E
Publicado no Neuro Oncol (2017)

DDIS-12. ONC201: THE FIRST SELECTIVE, NON-COMPETITIVE DRD2/3 ANTAGONIST FOR CLINICAL NEURO-ONCOLOGY

Por Vijay Prabhu, Varun, Madhukar, Neel, Anantharaman, Lakshmi, Sulli, Chidananda, Davidson, Edgar, Deacon, Sean, Tarapore, Rohinton, Rucker, Joseph, Charter, Neil, Doranz, Benjamin, Oster, Wolfgang, Stogniew, Martin, Elemento, Olivier, Free, R Benjamin, Sibley, David, Allen, Joshua
Publicado no Neuro Oncol (2018)

DDIS-20. IMIPRIDONE STRUCTURE ACTIVITY RELATIONSHIP UNCOVERS ONC206 AS THE NEXT BITOPIC DRD2 ANTAGONIST FOR ONCOLOGY WITH DIFFERENTIATED RECEPTOR PHARMACOLOGY

Por Prabhu, Varun, Cuoco, Caroline, Jung, Jinkyu, Rahman Kawakibi, Abed, Willette, Blair, Day, Marilyn, Anantharaman, Lakshmi, Charter, Neil, Rucker, Joseph, Doranz, Benjamin, Oster, Wolfgang, Stogniew, Martin, Gilbert, Mark, Benjamin Free, R, Sibley, David, Allen, Joshua
Publicado no Neuro Oncol (2019)

EXTH-33. RECEPTOR PHARMACOLOGY OF ONC201: THE FIRST BITOPIC DRD2 ANTAGONIST FOR CLINICAL NEURO-ONCOLOGY

Por Benjamin Free, R, Cuoco, Caroline, Prabhu, Varun, Willette, Blair, Day, Marilyn, Anantharaman, Lakshmi, Sulli, Chidananda, Davidson, Edgar, Deacon, Sean, Rucker, Joseph, Charter, Neil, Doranz, Benjamin, Oster, Wolfgang, Stogniew, Martin, Robert Lane, J, Sibley, David, Allen, Joshua
Publicado no Neuro Oncol (2019)

MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions

Por Grimes, Jak, Desai, Sapna, Charter, Neil W., Lodge, James, Moita Santos, Rita, Isidro‐Llobet, Albert, Mason, Andrew M., Wu, Zining, Wolfe, Lawrence A., Anantharaman, Lakshmi, Green, Andrew, Bridges, Angela M., Dalmas Wilk, Deidre A., Brown, Andrew J.
Publicado no Pharmacol Res Perspect (2019)

Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia

Por Nii, Takenobu, Prabhu, Varun V., Ruvolo, Vivian, Madhukar, Neel, Zhao, Ran, Mu, Hong, Heese, Lauren, Nishida, Yuki, Kojima, Kensuke, Garnett, Mathew J., McDermott, Ultan, Benes, Cyril H., Charter, Neil, Deacon, Sean, Elemento, Olivier, Allen, Joshua E., Oster, Wolfgang, Stogniew, Martin, Ishizawa, Jo, Andreeff, Michael
Publicado no Leukemia (2019)

EXTH-17. SELECTIVE, NON-COMPETITIVE DRD2/3 ANTAGONISM BY IMIPRIDONE ONC206 IS EFFECTIVE IN TUMORS WITH DOPAMINE RECEPTOR DYSREGULATION

Por Prabhu, Varun Vijay, Madhukar, Neel, Tarapore, Rohinton, Garnett, Mathew, McDermott, Ultan, Benes, Cyril, Anantharaman, Lakshmi, Charter, Neil, Deacon, Sean, VanEngelenburg, Alexander, Rucker, Joseph, Doranz, Benjamin, Rusert, Jessica, Wechsler-Reya, Robert, Elemento, Olivier, Stogniew, Martin, Oster, Wolfgang, DeMorrow, Sharon, Free, R Benjamin, Sibley, David, Allen, Joshua
Publicado no Neuro Oncol (2018)