EXTH-62. PRECLINICAL EFFICACY OF THE IMIPRIDONE ONC-206 AGAINST MEDULLOBLASTOMA

Treatment for medulloblastoma (MB) is typically ineffective for MYC amplified or metastatic SHH, Group 3 and 4 subgroups. Promising preclinical and clinical results have been obtained for adult and pediatric malignant glioma treated with ONC-201, a selective antagonist of DRD2, a G-protein coupled r...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: MacDonald, Tobey, Malhotra, Anshu, Liu, Jingbo, Zhang, Hongying, Schneiderjan, Matthew, Vega, Jose Velazquez, Prabhu, Varun, Allen, Joshua
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Preclinical Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650907/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.416
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