MODL-06. PRECLINICAL EFFICACY OF THE IMIPRIDONE ONC-206 AGAINST MEDULLOBLASTOMA

Treatment for medulloblastoma (MB) is typically ineffective for MYC amplified or metastatic SHH, Group 3 and 4 subgroups. Promising preclinical and clinical results have been obtained in brain cancers treated with ONC-201, a selective antagonist of DRD2, a G-protein coupled receptor that regulates p...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Malhotra, Anshu, Liu, Jingbo, Zhang, Hongying, Ma, Minhui, Vega, Jose Velazquez, Schniederjan, Matthew, Prabhu, Varun, Allen, Joshua, MacDonald, Tobey
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Preclinical Models/Experimental Therapy/Drug Discovery
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715948/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.582
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