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Overexpression of quality control proteins reduces prion conversion in prion-infected cells

Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). These diseases have the potential to transmit within or between species, including zoonotic transmiss...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Thapa, Simrika, Abdulrahman, Basant, Abdelaziz, Dalia H., Lu, Li, Ben Aissa, Manel, Schatzl, Hermann M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187620/
https://ncbi.nlm.nih.gov/pubmed/30154245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002754
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