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Overexpression of quality control proteins reduces prion conversion in prion-infected cells
Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). These diseases have the potential to transmit within or between species, including zoonotic transmiss...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187620/ https://ncbi.nlm.nih.gov/pubmed/30154245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002754 |
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