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An astrocyte cell line that differentially propagates murine prions

Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). Elucidating the molecular and cellular mechanisms underlying prion propagation may help to develop disease intervent...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tahir, Waqas, Abdulrahman, Basant, Abdelaziz, Dalia H., Thapa, Simrika, Walia, Rupali, Schätzl, Hermann M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450132/
https://ncbi.nlm.nih.gov/pubmed/32561641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012596
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