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Gene-edited murine cell lines for propagation of chronic wasting disease prions

Prions cause fatal infectious neurodegenerative diseases in humans and animals. Cell culture models are essential for studying the molecular biology of prion propagation. Defining such culture models is mostly a random process, includes extensive subcloning, and for many prion diseases few or no mod...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Walia, Rupali, Ho, Cheng Ching, Lee, Chi, Gilch, Sabine, Schatzl, Hermann M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673760/
https://ncbi.nlm.nih.gov/pubmed/31371793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47629-z
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