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Overexpression of quality control proteins reduces prion conversion in prion-infected cells
Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). These diseases have the potential to transmit within or between species, including zoonotic transmiss...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187620/ https://ncbi.nlm.nih.gov/pubmed/30154245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002754 |
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