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Cytotoxic and mutagenic properties of O(6)-alkyl-2′-deoxyguanosine lesions in Escherichia coli cells
Environmental exposure and cellular metabolism can give rise to DNA alkylation, which can occur on the nitrogen and oxygen atoms of nucleobases, as well as on the phosphate backbone. Although O(6)-alkyl-2′-deoxyguanosine (O(6)-alkyl-dG) lesions are known to be associated with cancer, not much is kno...
Uloženo v:
| Vydáno v: | J Biol Chem |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166734/ https://ncbi.nlm.nih.gov/pubmed/30068548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004676 |
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