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Cytotoxic and Mutagenic Properties of C3′-Epimeric Lesions of 2′-Deoxyribonucleosides in Escherichia coli Cells

Reactive oxygen species (ROS), resulting from endogenous metabolism and/or environmental exposure, can induce damage to the 2-deoxyribose moiety in DNA. Specifically, a hydrogen atom from each of the five carbon atoms in 2-deoxyribose can be abstracted by hydroxyl radical, and improper chemical repa...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Wang, Pengcheng, Amato, Nicholas J., Wang, Yinsheng
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615823/
https://ncbi.nlm.nih.gov/pubmed/28650656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00146
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