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Cytotoxic and mutagenic properties of minor-groove O(2)-alkylthymidine lesions in human cells
Endogenous metabolism, environmental exposure, and cancer chemotherapy can lead to alkylation of DNA. It has been well documented that, among the different DNA alkylation products, minor-groove O(2)-alkylthymidine (O(2)-alkyldT) lesions are inefficiently repaired. In the present study, we examined h...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986211/ https://ncbi.nlm.nih.gov/pubmed/29685891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003133 |
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