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Cytotoxic and mutagenic properties of alkyl phosphotriester lesions in Escherichia coli cells

Exposure to many endogenous and exogenous agents can give rise to DNA alkylation, which constitutes a major type of DNA damage. Among the DNA alkylation products, alkyl phosphotriesters have relatively high frequencies of occurrence and are resistant to repair in mammalian tissues. However, little i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wu, Jiabin, Wang, Pengcheng, Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934668/
https://ncbi.nlm.nih.gov/pubmed/29514270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky140
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