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Cytotoxic and mutagenic properties of O(4)-alkylthymidine lesions in Escherichia coli cells
Due to the abundant presence of alkylating agents in living cells and the environment, DNA alkylation is generally unavoidable. Among the alkylated DNA lesions, O(4)-alkylthymidine (O(4)-alkyldT) are known to be highly mutagenic and persistent in mammalian tissues. Not much is known about how the st...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678858/ https://ncbi.nlm.nih.gov/pubmed/26400162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv941 |
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