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Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O(2)-alkylthymidine lesions
Endogenous metabolism, environmental exposure, and treatment with some chemotherapeutic agents can all give rise to DNA alkylation, which can occur on the phosphate backbone as well as the ring nitrogen or exocyclic nitrogen and oxygen atoms of nucleobases. Previous studies showed that the minor-gro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176383/ https://ncbi.nlm.nih.gov/pubmed/25120272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku748 |
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