Llwytho...

Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O(4)-Alkylthymidine Lesions

O(2)- and O(4)-alkylated thymidine lesions are known to be poorly repaired and persist in mammalian tissues. To understand how mammalian cells sense the presence and regulate the repair of these lesions, we employed a quantitative proteomic method to discover regioisomeric O(2)- and O(4)-n-butylthym...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Chem
Prif Awduron: He, Xiaomei, Wang, Pengcheng, Wang, Yinsheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904241/
https://ncbi.nlm.nih.gov/pubmed/33290046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c04224
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