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In Vitro Lesion Bypass Studies of O(4)-Alkylthymidines with Human DNA Polymerase η

Environmental exposure and endogenous metabolism can give rise to DNA alkylation. Among alkylated nucleosides, O(4)-alkylthymidine (O(4)-alkyldT) lesions are poorly repaired in mammalian systems and may compromise the efficiency and fidelity of cellular DNA replication. To cope with replication-stal...

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Bibliografische gegevens
Gepubliceerd in:Chem Res Toxicol
Hoofdauteurs: Williams, Nicole L., Wang, Pengcheng, Wu, Jiabin, Wang, Yinsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615818/
https://ncbi.nlm.nih.gov/pubmed/27002924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00509
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