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Translesion synthesis of O(4)-alkylthymidine lesions in human cells
Environmental exposure, endogenous metabolism and cancer chemotherapy can give rise to alkylation of DNA, and the resulting alkylated thymidine (alkyldT) lesions were found to be poorly repaired and persistent in mammalian tissues. Unrepaired DNA lesions may compromise genomic integrity by inhibitin...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100597/ https://ncbi.nlm.nih.gov/pubmed/27466394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw662 |
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