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Translesion synthesis of O(4)-alkylthymidine lesions in human cells
Environmental exposure, endogenous metabolism and cancer chemotherapy can give rise to alkylation of DNA, and the resulting alkylated thymidine (alkyldT) lesions were found to be poorly repaired and persistent in mammalian tissues. Unrepaired DNA lesions may compromise genomic integrity by inhibitin...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100597/ https://ncbi.nlm.nih.gov/pubmed/27466394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw662 |
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