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Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O(4)-Alkylthymidine Lesions
O(2)- and O(4)-alkylated thymidine lesions are known to be poorly repaired and persist in mammalian tissues. To understand how mammalian cells sense the presence and regulate the repair of these lesions, we employed a quantitative proteomic method to discover regioisomeric O(2)- and O(4)-n-butylthym...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904241/ https://ncbi.nlm.nih.gov/pubmed/33290046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c04224 |
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