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Ada protein– and sequence context–dependent mutagenesis of alkyl phosphotriester lesions in Escherichia coli cells
Alkyl phosphotriester (alkyl-PTE) lesions are frequently induced in DNA and are resistant to repair. Here, we synthesized and characterized methyl (Me)- and n-butyl (nBu)-PTEs in two diastereomeric configurations (S(p) and R(p)) at six different flanking dinucleotide sites, i.e. XT and TX (X = A, C,...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7324520/ https://ncbi.nlm.nih.gov/pubmed/32381504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013657 |
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