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DNA replication studies of N-nitroso compound–induced O(6)-alkyl-2′-deoxyguanosine lesions in Escherichia coli
N-Nitroso compounds (NOCs) are common DNA-alkylating agents, are abundantly present in food and tobacco, and can also be generated endogenously. Metabolic activation of some NOCs can give rise to carboxymethylation and pyridyloxobutylation/pyridylhydroxybutylation of DNA, which are known to be carci...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422096/ https://ncbi.nlm.nih.gov/pubmed/30655287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007358 |
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