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DNA replication studies of N-nitroso compound–induced O(6)-alkyl-2′-deoxyguanosine lesions in Escherichia coli

N-Nitroso compounds (NOCs) are common DNA-alkylating agents, are abundantly present in food and tobacco, and can also be generated endogenously. Metabolic activation of some NOCs can give rise to carboxymethylation and pyridyloxobutylation/pyridylhydroxybutylation of DNA, which are known to be carci...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Wang, Pengcheng, Leng, Jiapeng, Wang, Yinsheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422096/
https://ncbi.nlm.nih.gov/pubmed/30655287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007358
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