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The roles of polymerases ν and θ in replicative bypass of O(6)- and N(2)-alkyl-2′-deoxyguanosine lesions in human cells
Exogenous and endogenous chemicals can react with DNA to produce DNA lesions that may block DNA replication. Not much is known about the roles of polymerase (Pol) ν and Pol θ in translesion synthesis (TLS) in cells. Here we examined the functions of these two polymerases in bypassing major-groove O(...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7135994/ https://ncbi.nlm.nih.gov/pubmed/32098870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012830 |
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