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DNA Polymerase II Supports the Replicative Bypass of N(2)-Alkyl-2′-deoxyguanosine Lesions in Escherichia coli Cells
Alkylation represents a main form of DNA damage. The N(2) position of guanine is frequently alkylated in DNA. The SOS-induced polymerases have been shown to be capable of bypassing various DNA damage products in Escherichia coli. Herein, we explored the influences of four N(2)-alkyl-dG lesions (alky...
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| Veröffentlicht in: | Chem Res Toxicol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7965357/ https://ncbi.nlm.nih.gov/pubmed/33417436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.0c00478 |
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