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The Impact of Minor-Groove N(2)‑Alkyl-2′-deoxyguanosine Lesions on DNA Replication in Human Cells
Endogenous metabolites and exogenous chemicals can induce covalent modifications on DNA, producing DNA lesions. The N(2) of guanine was shown to be a common alkylation site in DNA; however, not much is known about the influence of the size of the alkyl group in N(2)-alkyldG lesions on cellular DNA r...
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| Veröffentlicht in: | ACS Chem Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948715/ https://ncbi.nlm.nih.gov/pubmed/31347832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00129 |
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