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Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli.
The E. coli ada+ gene product that controls the adaptive response to alkylating agents has been purified to apparent homogeneity using an overproducing expression vector system. This 39 kDa protein repairs 0(6)-methylguanine and 0(4)-methylthymine residues in alkylated DNA by transfer of the methyl...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1985
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.8.2683 |
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