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Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli.
The E. coli ada+ gene product that controls the adaptive response to alkylating agents has been purified to apparent homogeneity using an overproducing expression vector system. This 39 kDa protein repairs 0(6)-methylguanine and 0(4)-methylthymine residues in alkylated DNA by transfer of the methyl...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1985
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC341187/ https://ncbi.nlm.nih.gov/pubmed/2987862 |
| Etykiety: |
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