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Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli.

The E. coli ada+ gene product that controls the adaptive response to alkylating agents has been purified to apparent homogeneity using an overproducing expression vector system. This 39 kDa protein repairs 0(6)-methylguanine and 0(4)-methylthymine residues in alkylated DNA by transfer of the methyl...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: McCarthy, T V, Lindahl, T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1985
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.8.2683
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