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Stereospecific removal of methyl phosphotriesters from DNA by an Escherichia coli ada+ extract.

The ada+ gene product, a DNA methyltransferase present in extracts from an Escherichia coli strain constitutive for the adaptive response, removes only half of the methyl phosphotriesters from alkylated DNA. Since DNA phosphotriesters occur in two isomeric configurations (denoted Rp and Sp), we exam...

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Main Authors: Weinfeld, M, Drake, A F, Saunders, J K, Paterson, M C
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC322023/
https://ncbi.nlm.nih.gov/pubmed/3903661
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