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High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing

Human cells are constantly exposed to environmental and endogenous agents which can induce damage to DNA. Understanding the implications of these DNA modifications in the etiology of human diseases requires the examination about how these DNA lesions block DNA replication and induce mutations in cel...

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Autori principali: Yuan, Bifeng, Wang, Jianshuang, Cao, Huachuan, Sun, Ruobai, Wang, Yinsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152323/
https://ncbi.nlm.nih.gov/pubmed/21470959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr159
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