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Cytotoxic and mutagenic properties of minor-groove O(2)-alkylthymidine lesions in human cells
Endogenous metabolism, environmental exposure, and cancer chemotherapy can lead to alkylation of DNA. It has been well documented that, among the different DNA alkylation products, minor-groove O(2)-alkylthymidine (O(2)-alkyldT) lesions are inefficiently repaired. In the present study, we examined h...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986211/ https://ncbi.nlm.nih.gov/pubmed/29685891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003133 |
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