Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia

Fanconi anemia (FA) is a bone marrow failure (BMF) syndrome that arises from mutations in a network of FA genes essential for DNA interstrand crosslink (ICL) repair and replication stress tolerance. While allogeneic stem cell transplantation can replace defective HSCs, interventions to mitigate HSC...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Balcerek, Joanna, Jiang, Jing, Li, Yang, Jiang, Qinqin, Holdreith, Nicholas, Singh, Brijendra, Chandra, Vemika, Lv, Kaosheng, Ren, Jian-gang, Rozenova, Krasimira, Li, Weihua, Greenberg, Roger A., Tong, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156422/
https://ncbi.nlm.nih.gov/pubmed/30254368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06380-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker