14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells

Hematopoietic stem and progenitor cell (HSPC) functions are governed by intricate signaling networks. The tyrosine kinase JAK2 plays an essential role in cytokine signaling during hematopoiesis. The adaptor protein LNK is a critical determinant of this process through its inhibitory interaction with...

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Autori principali: Jiang, Jing, Balcerek, Joanna, Rozenova, Krasimira, Cheng, Ying, Bersenev, Alexey, Wu, Chao, Song, Yiwen, Tong, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366400/
https://ncbi.nlm.nih.gov/pubmed/22546852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59719
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