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14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells
Hematopoietic stem and progenitor cell (HSPC) functions are governed by intricate signaling networks. The tyrosine kinase JAK2 plays an essential role in cytokine signaling during hematopoiesis. The adaptor protein LNK is a critical determinant of this process through its inhibitory interaction with...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366400/ https://ncbi.nlm.nih.gov/pubmed/22546852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59719 |
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